Expanded Publishing Model for Genetic Association Studies

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Expanded publishing model for genetic association studies.

To the Editors: While stressing the need to integrate epidemiology and biology for causal inference, new CEBP publication criteria will exclude the results of many genetic association studies (1). Clearly, editors must prioritize because journal pages are limited; at the same time, epidemiologists are able to measure thousands of genetic variants and potentially millions of gene-gene and gene-e...

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Publishing genetic association studies in Thorax

G enetic association studies have the potential to provide a valuable insight into disease mechanisms. However, many studies submitted to journals such as Thorax are underpowered or poorly designed. This has led to a number of journals providing guidance to investigators regarding the design of studies which would be considered for publication within the journal. In the editorial which follows ...

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Genetic association studies.

To the Editor: I am delighted to see that Arteriosclerosis, Thrombosis, and Vascular Biology has taken the lead in initiating an open discussion about genetic association studies in such a prominent manner. As correctly pointed out in the editorial by Dr Hegele,1 the number of publications has exponentially increased in the last decade. Despite the intrinsic problems with this approach, this ex...

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Genetic association studies.

With the completion of the HapMap project1 and the development of technology that allows the examination of 1 million genetic polymorphisms at once, genetic association studies are becoming more comprehensive. This article first provides a brief overview of the rationale for genetic association studies; it then discusses the primary features differentiating genetic from standard association stu...

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The widespread availability of DNA from large population studies, the development of rapid throughput genotyping assays, and the identification of numerous polymorphisms in genes of interest make it easier to perform genetic association studies in humans. We consider these studies appropriate areas of research in relation to atherosclerosis, thrombosis, and vascular biology. In this issue, Drs ...

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ژورنال

عنوان ژورنال: Cancer Epidemiology Biomarkers & Prevention

سال: 2006

ISSN: 1055-9965,1538-7755

DOI: 10.1158/1055-9965.epi-05-0733